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Research

Contents:

"Everything I Eat Turns into Fat" by Cynthia K. Buffington, Ph.D.

Causes for Food Addiction by Cynthia K. Buffington, Ph.D.


"Everything I Eat Turns into Fat"

By Cynthia K. Buffington, Ph.D.

Have you noticed how fast you are capable of gaining weight if you do not watch the amount and type of foods that you eat? Do you feel as though everything you eat turns into fat? Well, actually, that statement may not be that far from the truth.

Weight gain and excessive obesity cause the body to become highly efficient in storing fat. Obesity increases the ability of adipose (fat) tissue to store fat in order to protect other tissues from the toxic effects of high fat in the blood stream, a condition known as lipid toxicity.

Adipose tissue is the only tissue in the body with the capacity to store large amounts of fat. Other tissues are capable of storing tiny amounts of fat for the purpose of maintaining membranes, providing fuel for energy, producing hormones or for various other functions. However, none of these tissues are designed to take up, store, or utilize the large amounts of fat circulating in the blood of many individuals with extreme obesity, and an overload of fat in these tissues has toxic consequences.

Exposure of the liver to high amounts of fat causes metabolic changes that contribute to the development of fatty liver disease, diabetes and coronary artery disease. Fat overload of heart cells may not only cause these cells to self-destruct but also cause cardiomyopathy and heart failure. High fat also leads to self-destruction of specific cells of the pancreas (beta cells) that secrete insulin, causing insufficient production of insulin and diabetes. In muscle, fat overload may cause insulin resistance, a condition that significantly contributes to the development of various obesity-associated diseases, including coronary artery disease, diabetes, gout, hypertension, and progressive liver disease (non-alcoholic steatohepatitis).

In an effort to protect the body against the toxic effects of fat, the amount of adipose tissue and its capacity for fat storage is substantially increased. With obesity, the enzyme needed for the uptake of circulating fat into adipose tissue is enhanced and the breakdown of stored fat is reduced, thereby lowering the amount of fat in the circulation. Furthermore, severe obesity is associated with an expansion of adipose tissue resulting from an increase in the replication of adipose tissue (fat) cells and a reduction in rates at which these cells self-destruct.

With massive weight loss, a substantial reduction in adipose tissue occurs but, at the same time, there remains the increased potential for fat accumulation caused by the high numbers and altered metabolism of fat cells. The bariatric patient, therefore, must be ever mindful of the need to comply with their postoperative dietary regimen. Even short periods of ‘cheating’ could cause rapid weight gain because many of the calories over-consumed are literally being ‘turned into fat’.


Causes for Food Addiction

By Cynthia K. Buffington, Ph.D.

Millions of Americans suffer from addictions involving alcohol, nicotine, and drugs. For some individuals, food is also an addiction. Recent studies found that food addiction, drug abuse, and other self-destructive behaviors have similar underlying neurochemical and behavioral characteristics.

One of the most common behavioral characteristics of individuals suffering from self-destructive addictions (overeating, drinking, smoking, using drugs, etc.) is a feeling of ‘not being good enough’. Feelings of low self-worth, in turn, may cause low self-esteem, a poor body image, depression, anxiety, a need to overachieve, and an intense and chronic fear of failure.

The ‘addict’ not only has negative feelings regarding themselves, but also has failed to develop appropriate stress coping behavior to deal with such feelings. Instead of confronting life stressors directly or finding healthy ways to manage emotions (exercise, journaling, relaxation, spiritual care, therapy, etc.), the ‘addict’ seeks to avoid unpleasant feelings by eating, drinking alcohol, smoking, using drugs, gambling, and various other ways of escaping from reality.

Emotional distress and avoidance stress coping behavior can produce neurochemical changes in the limbic system of the brain, which is the area of the brain that controls mood and basic functions such as eating. The addict often has overactive stress hormone responses within the limbic system that impair the actions of specific brain messengers, (i.e. serotonin, dopamine) that, in turn, cause depression, food cravings (particularly for carbohydrates), overeating, compulsive  behaviors (such as binge eating), substance dependencies, and an increased risk for multiple addictions.

Reduced mood, caused by such neurochemical defects, can be reversed, at least temporarily, by eating certain foods or by using alcohol, nicotine, and drugs. Eating carbohydrates (sweets in particular) helps to improve mood by increasing the neurochemical messenger, serotonin. And, eating sweets, fat, or even smelling one’s favorite food improves mood by enhancing the actions of another neurochemical, dopamine, which is also responsible for the ‘good feelings’ associated with drugs and alcohol.

The food ‘addict’ may, therefore, be overeating in an attempt to improve their mood. But, overeating may, similar to frequent use of drugs or alcohol, blunt the responses of these ‘feel good’ neurochemical pathways to food, requiring the individual to eat more to achieve satisfaction. At this point, the individual not only eats in an effort to establish emotional stability but also has a physical need to do so and, thereby, feels powerless over food.

Abstinence from the abused substance helps to reverse or improve many of the neurochemical defects associated with addictions. Bariatric surgery, by limiting the amount of food and type of food that can be consumed, and by enhancing mood through the joy of weight loss, is also effective in improving neurochemical defects contributing to addictive behavior. However, such improvements are often short-lived. Food cravings, as well as depression, may reoccur over time, along with weight gain.

The neurochemical defects contributing to food dependency among post-bariatric surgical patients may reappear over time because the behaviors responsible for initiating the cascade of events leading to such defects are not resolved by the surgery, those being low self-worth and poor stress coping skills. It is, therefore, of utmost importance for the overall wellbeing and long-term weight loss success of the bariatric patient that aftercare bariatric programs be designed to help individuals recognize their own self-worth and learn healthful ways of dealing with emotional stress.

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